In these two sessions, held on July 1 and 2, the Conceptual Framework for the Protection of Vulnerable Migrants, the IOM Model of Determining Factors for Migrant Vulnerability, as well as the Update of the Regional Guidelines for the Preliminary Identification of Profiles and Reference Mechanisms on Migrant Populations in Vulnerable Situations were presented.

On July 29 and 30, the First Meeting of the Regional Consultation Group on Migration was held in the City of Puebla in a hybrid format (virtual - face-to-face). During these two days of work, topics of interest were addressed, and dialogue was fostered among the 11 Member Countries, alongside observer organizations and representatives of civil society. The first day of work was attended by Alejandro Encinas Rodríguez, Undersecretary of Human Rights, Population and Migration, and President Pro-Tempore of the RCM. He was accompanied by the Undersecretary of Employment and Labor Productivity, Marath Baruch Bolaños López, and the distinguished presence of the Governor of the State of Puebla, Miguel Barbosa Huerta.

On August 18, 19, and 20, the Training Program in Migration Policies and Governance with a focus on local and municipal levels was held. The objective of this activity was to strengthen the capacities of civil actors at the local level in the RCM Member Countries, in terms of the design, implementation, and evaluation of migration public policies, to improve migration governance. The program was developed through a combination of various techniques, which included a virtual self-learning course on migration trends in Latin America, as well as presentations by experts, spaces for dialogue, and presentations by representatives of local governments of the Member Countries.

On August 25 and 26, the 'XIX South American Conference on Migration (SACM)' was held virtually, and it was attended by Mexico as an observer country on behalf of the Pro-Tempore Presidency of the Regional Conference on Migration (RCM). The commitment of this regional mechanism to continue collaborating with the entire continent in favor of migrants and address common issues like migration governance in the region, the inclusion of migrants in situations of vulnerability, and the promotion of gender perspective was reiterated. Likewise, Pro-Tempore Presidency of the RCM welcomed the government of the Republic of Chile as the upcoming Pro-Tempore Presidency of the SACM.

On September 9 and 10, the II Plenary Meeting between the RCM and the SACM was held. The objectives of this meeting were: promote greater collaboration between the countries of both regional processes to address hemispheric challenges related to migration governance, including irregular and extra-regional migration, and identify specific problems that require attention to deter irregular migration and promote regular migration, and identify concrete next steps to address these issues. As a result of this meeting, a joint communiqué was issued, among other materials.

On September 17, 2021, from 9:00 a.m. to 11:00 a.m., the workshop on the review of the Global Compact on Migration (GCM) was held, in which general aspects of the work of the United Nations Network on Migration were presented. In support of the Global Compact for Safe, Orderly, and Regular Migration, the Member Countries determined actions to follow up on the GCM and dialogue was held on the contributions of the RCM to the revision of the GCM to be held in 2022.